SR-9009 (Stenabolic)

Scientific Overview

SR-9009, commonly known as Stenabolic, is a synthetic compound classified as a REV-ERB agonist. In preclinical research settings, it has been studied for its role in regulating circadian rhythm pathways, metabolic activity, and mitochondrial function.

REV-ERB receptors are nuclear receptors involved in the control of gene expression linked to metabolism, inflammation, and biological clock regulation. SR-9009 is used in laboratory environments to help researchers better understand these biological systems.

Research Applications

SR-9009 has been investigated in experimental models for its effects on:

• Circadian rhythm regulation
• Metabolic gene expression
• Lipid metabolism pathways
• Energy expenditure signaling
• Mitochondrial activity in preclinical models
• Nuclear receptor biology (REV-ERBα and REV-ERBβ)

These applications are strictly limited to scientific and laboratory research.

Mechanism of Action

SR-9009 functions as an agonist of the REV-ERBα receptor, a key component of the molecular circadian clock. Activation of this receptor influences the expression of genes involved in metabolic regulation, inflammation control, and energy balance.

By modulating REV-ERB signaling, researchers can study how circadian rhythms interact with metabolic pathways in controlled experimental settings.

Current Scientific Status

SR-9009 remains an investigational compound used exclusively in research environments.

• Not approved for clinical or therapeutic use
• Not intended for human consumption
• Used only for laboratory and preclinical studies
• Subject to ongoing scientific investigation

Researchers should always comply with institutional guidelines and regulatory requirements when handling this compound.

Safety & Handling Information

SR-9009 should only be handled by qualified professionals in controlled laboratory environments.

• Research use only (RUO)
• Not for diagnostic or therapeutic use
• Proper PPE and laboratory safety procedures required
• Safety Data Sheet (SDS) should be reviewed before handling
• Must comply with institutional biosafety standards

Frequently Asked Questions

What is SR-9009 used for in research?

SR-9009 is used in laboratory studies focused on circadian rhythm, metabolism, and REV-ERB receptor signaling.

Does SR-9009 affect the body clock?

In research models, SR-9009 interacts with REV-ERB receptors involved in circadian rhythm regulation.

Is SR-9009 approved for human use?

No. It is not approved for medical or human use and is strictly for research purposes.

Why is SR-9009 studied?

It is studied to better understand metabolic regulation, gene expression, and biological clock mechanisms.

Learn More

For additional scientific information, researchers typically refer to peer-reviewed journals and biomedical databases focused on endocrinology, metabolism, and circadian biology.